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首页-小分子抑制剂&激动剂-Others-Pyruvate Kinase-PKM2 aggregates inhibitor K27
PKM2 aggregates inhibitor K27

Chemical Structure : PKM2 aggregates inhibitor K27

CAS No.: 2602406-58-4

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PKM2 aggregates inhibitor K27 (PKM2 aggregate-dissolving compound K27)

货号: PC-22681Not For Human Use, Lab Use Only.

PKM2 aggregates inhibitor K27 is a small molecule capable of dissolving PKM2 aggregates and alleviating senescence, restores PKM2 enzymatic activity and glycolytic flux, delays aging of naturally and prematurely aged mice.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PKM2 aggregates inhibitor K27 is a small molecule capable of dissolving PKM2 aggregates and alleviating senescence, restores PKM2 enzymatic activity and glycolytic flux, delays aging of naturally and prematurely aged mice.

物理化学性质&存储条件

分子量 530.65
分子式 C24H23FN4O3S3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

pyridin-3-ylmethyl 4-(4-((4-fluorophenyl)sulfonamido)benzoyl)piperazine-1-carbodithioate

参考文献

1. Juntao Bie, et al. Nat Commun. 2024 Jul 9;15(1):5761.

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