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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Isocitrate Dehydrogenase (IDH)

Request The Product List ofIsocitrate Dehydrogenase (IDH) Isocitrate Dehydrogenase (IDH)

Cat. No. Product Name Information
PC-45550

Ivosidenib

mutant IDH1 inhibitor

Ivosidenib (AG-120) is a potent, mutant-selective inhibitor of IDH1 (isocitrate dehydrogenase type 1) with IC50 of 12 nM for mouse IDH1 R132H.
PC-20532

IDH2 R140Q inhibitor CP-17

IDH2 R140Q inhibitor

IDH2 R140Q inhibitor CP-17 is a potent, selective inhibitor of IDH2 R140Q mutation with IC50 of 40.75 nM, 50-fold selectivity over wild-type IDH1/2.

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