Mas-related G protein-coupled receptor (MRGPR) (inhibitors, antagonists, agonists)-Probechem Biochemicals

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Cat. No.	Product Name	Information
PC-38069	MS47134 MRGPRX4 agonist	MS47134 is a potent, selective MRGPRX4 agonist with EC50 of 149 nM.
PC-38068	MRGPRX2 antagonist C9 MRGPRX2 inhibitor	MRGPRX2 antagonist C9 is a potent and selective MRGPRX2 inverse agonist (antagonist) with Ki of 43 nM.
PC-38067	ZINC16991592 MRGPRX2 inhibitor	ZINC16991592 (ZINC1592) is a selective MRGPRX2 antagonist with Ki of 189 nM.
PC-38066	MRGPRX1 agonist 1 MRGPRX1 agonist	MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors.
PC-62228	ZINC-3573 racemate MRGPRX2 agonist	ZINC-3573 racemate is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=3 uM), showing little activity against 315 other GPCRs and 97 representative kinases.
PC-62227	(R)-ZINC-3573 MRGPRX2 agonist	(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases.
PC-26492	AR234958 Mas1 agonist	AR234958 is a selective pharmacological activator of orphan GPCR Mas1 with pEC50 of 6.71, demonstrates superior efficacy compared to the peptide ligands NPFF, Ang-(1-7).
PC-24415	Cortistatin-14 TFA MRGPRX2 agonist	Cortistatin-14 TFA (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM.
PC-24414	Cortistatin-14 MRGPRX2 agonist	Cortistatin-14 (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM.
PC-24411	AR244555 Mas inverse agonist	AR244555 is a specific, non-peptide inverse agonist of G protein-coupled receptor Mas with IC50 of 186 and 348 nM for human and rat Mas receptor respectively.
PC-24183	Setomagpran MRGPRX2 antagonist	Setomagpran is a potent, selective antagonist of Mas-related G-protein receptor X2 (MRGPRX2) with anti-inflammatory activity.
PC-23468	MRGPRX2 antagonist Compound B MRGPRX2 antagonist	MRGPRX2 antagonist Compound B is a potent, selective MRGPRX2 antagonist with IC50 of 2.9 nM for inhibition of cortistatin 14-mediated MRGPRX2 activation.

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