Farnesyl transferase (FTase) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofFarnesyl transferase (FTase) Farnesyl transferase (FTase)

Cat. No.	Product Name	Information
PC-21769	Lonafarnib FTase inhibitor	Lonafarnib (SCH 66336) is a potent, orally bioavailable farnesyl protein transferase (FTase, farnesyltransferase) inhibitor with IC50 of 1.9 nM for H-Ras processing in whole cells.
PC-73014	FGTI-2734 Dual FT-GGT1 inhibitor	FGTI-2734 (FGTI2734) is a potent, CAAX tetrapeptide RAS C-terminal mimetic as dual farnesyltransferase (FT) and geranylgeranyltransferase-1 (GGT-1) inhibitor with IC50 of 250 and 520 nM, respectively.
PC-35110	ABT-100 FTase inhibitor	ABT-100 (ABT100) is a highly selective, potent, orally bioavailable inhibitor of farnesyltransferase (FTase).
PC-63362	LB42908 FTase inhibitor	LB42908 is a highly potent, selective, orally active inhibitor of Ras farnesyltransferase (FTase) with IC50 of 0.9 nM against H-Ras and 2.4 nM against K-Ras..
PC-42625	Tipifarnib S enantiomer	Tipifarnib S enantiomer is a potent and selective inhibitor of FTase (farnesyltransferase).
PC-42624	Tipifarnib FTase inhibitor	Tipifarnib ((IND 58359, R115777) is a potent and selective inhibitor of FTase (farnesyltransferase) with IC50 of 0.86 nM.
PC-44767	FTI-277 hydrochloride	FTI-277 hydrochloride is a peptide mimetic of the C-terminal Cys-Val-Ile-Met of K-Ras4B that potently inhibits FTase (Farnesyltransferase) with IC50 of 0.5 nM.
PC-44766	FTI-277 FTase inhibitor	FTI-277 is a peptide mimetic of the C-terminal Cys-Val-Ile-Met of K-Ras4B that potently inhibits FTase (Farnesyltransferase) with IC50 of 0.5 nM.
PC-23307	A-176120 FTase inhibitor	A-176120 is a potent, selective inhibitor of farnesyltransferase (FTase) with IC50 of 1.2 nM, inhibits Ras processing in H-ras-transformed NIH3T3 cells and HCT116 K-ras-mutated cells (ED50=1.6 and 0.5 uM, respectively).
PC-22630	FTI-2148 FTase inhibitor	FTI-2148 is a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM, >1000-fold selective over GGTase I.
PC-22629	FTI-2153 FTase inhibitor	FTI-2153 is the methylester prodrug of FTI-2148, a potent, selective farnesyltransferase (FTase) inhibitor with IC50 of 1.4 nM.

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