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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-ATP Citrate Lyase (ACL, ACLY)

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Cat. No. Product Name Information
PC-20106

ACLY inhibitor 326E

ATP citrate lyase inhibitor

ACLY inhibitor 326E is a potent ACLY inhibitor with IC50 of 5.31 uM, reduces de novo lipogenesis, and increases cholesterol efflux in vitro and in vivo.
PC-36165

NDI-091143

ATP citrate lyase inhibitor

NDI-091143 (NDI091143) is a potent, small-molecule inhibitor of human ATP-citrate lyase (ACLY) with Ki of 7.0 nM and IC50 of 2.1 nM in the ADP-Glo assays.
PC-62188

SB204990

ATP citrate lyase inhibitor

SB204990 is the cell-penetrant, orally active gamma-lactone prodrug of the potent ATP citrate-lyase (ACLY) inhibitor SB-201076.
PC-43001

Bempedoic acid

ATP citrate lyase inhibitor

Bempedoic acid (ESP-55016; ETC-1002) is a small molecule regulator of lipid and carbohydrate metabolism, inhibits ATP Citrate Lyase (ACL, ACLY).

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