dGPX4 | GPX4 PROTAC | Probechem Biochemicals

Chemical Structure : dGPX4

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dGPX4 (GPX4 PROTAC)

货号: PC-26132Not For Human Use, Lab Use Only.

dGPX4 is a potent GPX4 PROTAC degrader, depletes GPX4 via proteasomal protein degradation, induces cell-selective ferroptosis by targeting cancer cell microenvironment.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

dGPX4 is a potent GPX4 PROTAC degrader, depletes GPX4 via proteasomal protein degradation, induces cell-selective ferroptosis by targeting cancer cell microenvironment.

物理化学性质&存储条件

分子量	975.90
分子式	C46H48Cl2N8O10S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-chloro-N-(3-chloro-4-((1-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-N-(2-oxo-2-(phenethylamino)-1-(thiophen-2-yl)ethyl)acetamide

参考文献

1. Tianli Luo, et al. Angew Chem Int Ed Engl. 2022 Sep 26;61(39):e202206277.