dCK1α-1 | CK1α degrader | Probechem Biochemicals

Chemical Structure : dCK1α-1

加入收藏

货号: PC-23542Not For Human Use, Lab Use Only.

dCK1α-1 (LC-04-087) is a potent and selective CK1α-targeting molecular glue degrader with DC50 of 12 nM, Dmax of 90% in MOLM13 cells (72 h).

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

dCK1α-1 (LC-04-087) is a potent and selective CK1α-targeting molecular glue degrader with DC50 of 12 nM, Dmax of 90% in MOLM13 cells (72 h).

分子量	395.80
分子式	C19H14ClN5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-(5-(3-chloropyrazolo[1,5-a]pyrimidin-5-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

1. Lu Huang, et al. JACS Au. 2024 Nov 8;4(11):4423-4434.