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首页-抗体药物偶连体和PROTACs-PROTAC-dBRD4-BD1
dBRD4-BD1

Chemical Structure : dBRD4-BD1

CAS No.: 2839318-19-1

dBRD4-BD1 (BRD4 PROTAC)

货号: PC-49367Not For Human Use, Lab Use Only.

dBRD4-BD1 is a potent, selective degrader of BRD4 with DC50 of 280 nM, Dmax 77%.

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5 mg ¥4980 In stock
10 mg ¥7880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

dBRD4-BD1 is a potent, selective degrader of BRD4 with DC50 of 280 nM, Dmax 77%.

物理化学性质&存储条件

分子量 967.016
分子式 C50H53F3N8O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-N-(2-(2-(2-(4-(5-(2-(5-isopropyl-2-methylphenoxy)pyrimidin-4-yl)-4-(4-(trifluoromethyl)phenyl)-1H-imidazol-1-yl)piperidin-1-yl)ethoxy)ethoxy)ethyl)acetamide

参考文献

1. Anand Divakaran, et al. ACS Medicinal Chemistry Letters. 2022.

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