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首页-抗体药物偶连体和PROTACs-PROTAC-ZXH-1-161
ZXH-1-161

Chemical Structure : ZXH-1-161

CAS No.: 2407654-51-5

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ZXH-1-161

货号: PC-47018Not For Human Use, Lab Use Only.

ZXH-1-161 is a potent, selective small-molecule GSPT1 degrader, inhibits ceell viability in MM1.S with IC50 of 39 nM.

规格 价格 库存 数量
5 mg ￥2180 In stock
10 mg ￥3580 In stock
25 mg ￥5980 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ZXH-1-161 is a potent, selective small-molecule GSPT1 degrader, inhibits ceell viability in MM1.S with IC50 of 39 nM.
ZXH-1-161 is a superior tool to CC-885 for exploring the therapeutic potential of GSPT1 degradation and may provide additional opportunities for therapeutically targeting GSPT1.

物理化学性质&存储条件

分子量 468.52
分子式 C26H24N6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(4-((2-((2,3-dihydro-1H-inden-5-yl)amino)pyrimidin-4-yl)amino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

参考文献

1. Chelsea E Powell, et al. ACS Chem Biol. 2020 Oct 16;15(10):2722-2730.

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