ZD7114 | beta-adrenoceptor agonist | Probechem Biochemicals

Chemical Structure : ZD7114

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ZD7114 (ICI D7114, ZD 7114)

货号: PC-21223Not For Human Use, Lab Use Only.

ZD7114 (ICI D7114) is a potent, selective beta-adrenoceptor agonist, selectively stimulates brown fat and increases whole-body oxygen consumption.

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生物&药学活性

ZD7114 (ICI D7114) is a potent, selective beta-adrenoceptor agonist, selectively stimulates brown fat and increases whole-body oxygen consumption.
Treatment of rats with ICI D7114 stimulated oxygen consumption (ED50, 0.04 mg kg-1, p.o.) and BAT mitochondrial guanosine diphosphate (GDP)-binding (ED50, 0.15 mg kg-1, p.o.) with no chronotropic effects on the heart at these doses.
ZD7114 has activity at atypical beta-adrenoceptors in brown adipose tissue leading to increased whole body oxygen consumption.

物理化学性质&存储条件

分子量	418.49
分子式	C22H30N2O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-[2-Hydroxy-3-phenoxypropylaMinoethoxy]-N-(2-Methoxyethyl)phenoxyacetaMide

参考文献

1. Holloway BR, et al. Br J Pharmacol. 1991 Sep;104(1):97-104.

ZD7114 (ICI D7114, ZD 7114)

生物&药学活性

物理化学性质&存储条件

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ZD7114 (ICI D7114, ZD 7114)

生物&药学活性

物理化学性质&存储条件

参考文献

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