Z62954982 |CAS:1090893-12-1 Probechem Biochemicals

Chemical Structure : Z62954982

CAS No.: 1090893-12-1

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Z62954982 (Z 62954982)

货号: PC-63241Not For Human Use, Lab Use Only.

Z62954982 is a potent, specific Rac1 inhibitor, reduces the intracellular levels of Rac1-GTP in a concentration-dependent manner with IC50 of 12 uM, 4 times more effective than NSC23766 (IC50=50 uM).

规格	价格	库存
5 mg	￥980	In stock
10 mg	￥1380	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Z62954982 is a potent, specific Rac1 inhibitor, reduces the intracellular levels of Rac1-GTP in a concentration-dependent manner with IC50 of 12 uM, 4 times more effective than NSC23766 (IC50=50 uM).
Z62954982 causes a concentration-dependent decrease in transendothelial electrical resistance (TER) in both HDMEC and HUVEC.

物理化学性质&存储条件

分子量	415.464
分子式	C20H21N3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((3,5-Dimethylisoxazol-4-yl)methoxy)-N-(4-methyl-3-sulfamoyl-phenyl)benzamide

参考文献

1. Zhang XE, et al. PLoS One. 2016 May 17;11(5):e0155490.

2. Lobastova L, et al. Cell Oncol (Dordr). 2017 Feb;40(1):63-76.

3. Yamaguchi N, et al. Sci Rep. 2015 Jan 7;5:7656.

4. Ferri N, et al. J Med Chem. 2009 Jul 23;52(14):4087-90.

Z62954982 (Z 62954982)

生物&药学活性

物理化学性质&存储条件

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Z62954982 (Z 62954982)

生物&药学活性

物理化学性质&存储条件

参考文献

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