Yohimbine |CAS:146-48-5 Probechem Biochemicals

Chemical Structure : Yohimbine

CAS No.: 146-48-5

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Yohimbine

货号: PC-43161Not For Human Use, Lab Use Only.

Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.

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生物&药学活性

Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.
Yohimbine shows moderate affinity for the α1 receptor, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, 5-HT2B, and D2 receptors, and weak affinity for the 5-HT1E, 5-HT2A, 5-HT5A, 5-HT7, and D3 receptors.

物理化学性质&存储条件

分子量	354.4427
分子式	C21H26N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16α,17α)-

参考文献

1. Millan MJ, et al. Synapse. 2000 Feb;35(2):79-95.

2. Arthur JM, et al. Biochem Pharmacol. 1993 Jun 9;45(11):2337-41.

3. Pérez Piñero C, et al. Br J Pharmacol. 2012 May;166(2):721-36.

4. Baxter GS, et al. Br J Pharmacol. 1994 May;112(1):323-31.

Yohimbine

生物&药学活性

物理化学性质&存储条件

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Yohimbine

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