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首页-抗体药物偶连体和PROTACs-PROTAC-YZ268
YZ268

Chemical Structure : YZ268

CAS No.:

YZ268 (YZ-268, HDAC6 Degrader 13f)

货号: PC-72092Not For Human Use, Lab Use Only.

HDAC6 Degrader 13f (YZ268) is a selective HDAC6 degrader (PROTAC) with high potency, specific chemical probe to knock-down HDAC6.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    HDAC6 Degrader 13f (YZ268) is a selective HDAC6 degrader (PROTAC) with high potency, specific chemical probe to knock-down HDAC6.

    物理化学性质&存储条件

    分子量 884.05
    分子式 C49H57N9O7
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 Month
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((1-butyl-3-(4-((7-(4-(((4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)benzyl)amino)methyl)-1H-1,2,3-triazol-1-yl)heptyl)oxy)phenyl)ureido)methyl)-N-hydroxybenzamide

    参考文献

    1. Ka Yang, et al. Cell Chem Biol. 2020 Jul 16;27(7):866-876.e8.

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