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首页-抗体药物偶连体和PROTACs-PROTAC-YZ167
YZ167

Chemical Structure : YZ167

CAS No.:

YZ167 (YZ 167)

货号: PC-22938Not For Human Use, Lab Use Only.

YZ1678 is a potent, selective HDAC6 PROTAC degrader with DC50 of 1.94 nM in MM.1S cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

YZ1678 is a potent, selective HDAC6 PROTAC degrader with DC50 of 1.94 nM in MM.1S cells.

物理化学性质&存储条件

分子量 615.69
分子式 C33H37N5O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-(2-(4-((5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pent-4-yn-1-yl)oxy)benzylidene) hydrazineyl)-N-hydroxy-8-oxooctanamide

参考文献

1. Ka Yang, et al. Cell Chem Biol. 2020 Jul 16;27(7):866-876.e8.

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