WW-210 | STAT6 PROTAC | Probechem Biochemicals

Chemical Structure : WW-210

加入收藏

WW-210 (WW210)

货号: PC-28561Not For Human Use, Lab Use Only.

WW-210 is a potent, selective, and orally efficacious STAT6 PROTAC degrader with DC50 of 0.025 nM in Jurkat cells and 0.018 nM in hPBMC.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

WW-210 is a potent, selective, and orally efficacious STAT6 PROTAC degrader with DC50 of 0.025 nM in Jurkat cells and 0.018 nM in hPBMC.
WW-210 show high selectivity window over the other tested STAT family members.
WW-210 exhibits oral bioavailability, and effective STAT6 degradation in blood and spleen.
WW-210 alleviated skin lesions, reduced serum IgE, restored filaggrin expression, and decreased mast cell infiltration in mouse model of AD.

物理化学性质&存储条件

分子量	923.06
分子式	C51H55FN10O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(1-(3-(1H-Pyrazol-1-yl)propanoyl)-1,2,5,6-tetrahydropyridin-3-yl)-4-(4-(4-((1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidin-4-yl)methyl)piperazin-1-yl)phenyl)-7-fluoro-N,N-dimethyl-1H-indole-2-carboxamide

参考文献

1. Wang W, et al. J Med Chem. 2026 Oct 8;69(19):22102-22137.

WW-210 (WW210)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

WW-210 (WW210)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.