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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-WJM228
WJM228

Chemical Structure : WJM228

CAS No.: 2920880-95-9

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WJM228 (WJM-228)

货号: PC-20289Not For Human Use, Lab Use Only.

WJM228 (WJM-228) is a potent selective inhibitor of P. falciparum cytochrome bc1, targets the Qo site of cytochrome b (cyt b), shows potent parasite activity against P. falciparum 3D7 with EC50 of 19 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    WJM228 (WJM-228) is a potent selective inhibitor of P. falciparum cytochrome bc1, targets the Qo site of cytochrome b (cyt b), shows potent parasite activity against P. falciparum 3D7 with EC50 of 19 nM.

    物理化学性质&存储条件

    分子量 370.43
    分子式 C20H23FN4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-ethyl-6-fluoro-3-(3-methyl-1,2,4-oxadiazol-5-yl)-7-(4-methylpiperidin-1-yl)quinolin-4(1H)-one

    参考文献

    1. William Nguyen, et al. ACS Infect Dis. 2023 Mar 10;9(3):668-691.

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