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首页-抗体药物偶连体和PROTACs-PROTAC-WEE1 degrader 1
WEE1 degrader 1

Chemical Structure : WEE1 degrader 1

CAS No.:

WEE1 degrader 1

货号: PC-22390Not For Human Use, Lab Use Only.

WEE1 degrader 1 is a potent, selective CRBN-dependent WEE1 molecular glue degrader with DC50 of 91 nM, does not degrade CK1α.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

WEE1 degrader 1 is a potent, selective CRBN-dependent WEE1 molecular glue degrader with DC50 of 91 nM, does not degrade CK1α.

物理化学性质&存储条件

分子量 403.40
分子式 C21H17N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(5-(2-aminoimidazo[1,2-a]pyridine-3-carbonyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

参考文献

1. Razumkov H, et al. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592550.

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