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首页-抗体药物偶连体和PROTACs-PROTAC-WEE1/CK1α degrader 2
WEE1/CK1α degrader 2

Chemical Structure : WEE1/CK1α degrader 2

CAS No.:

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WEE1/CK1α degrader 2

货号: PC-22393Not For Human Use, Lab Use Only.

WEE1/CK1α degrader 2 is a highly potent WEE1/CK1α molecular glue degrader with DC50 of 1.6/1.5 nM, respectively, Emax >98%.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

WEE1/CK1α degrader 2 is a highly potent WEE1/CK1α molecular glue degrader with DC50 of 1.6/1.5 nM, respectively, Emax >98%.

物理化学性质&存储条件

分子量 537.62
分子式 C31H31N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(5-(2-(adamantan-1-ylamino)imidazo[1,2-a]pyridine-3-carbonyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

参考文献

1. Razumkov H, et al. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592550.

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