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首页-小分子抑制剂&激动剂-GPCR-mAChR-VU6069863
VU6069863

Chemical Structure : VU6069863

CAS No.: 3106590-94-4

VU6069863 (VU-6069863)

货号: PC-28266Not For Human Use, Lab Use Only.

VU6069863 is a potent, selective M1 positive allosteric modulator (PAM) with EC50 of 226 nM and 140 nM for hM1 and rM1, shows minimal M1 agonism.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VU6069863 is a potent, selective M1 positive allosteric modulator (PAM) with EC50 of 226 nM and 140 nM for hM1 and rM1, shows minimal M1 agonism.

物理化学性质&存储条件

分子量 348.40
分子式 C21H20N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8,9-dimethyl-7-(4-(oxazol-4-yl)benzyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one

参考文献

1. Changho Han, et al. ACS Med Chem Lett. 2026 Aug 21;17(9):2085-2094.

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