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首页-小分子抑制剂&激动剂-GPCR-mAChR-VU6009003
VU6009003

Chemical Structure : VU6009003

CAS No.: 2135885-84-4

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VU6009003 (VU 6009003)

货号: PC-63278Not For Human Use, Lab Use Only.

VU6009003 is a potent, selective, CNS penetrant mAChR M4 positive allosteric modulator with EC50 of 197 nM and 437 nM for human and rat M4, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    VU6009003 is a potent, selective, CNS penetrant mAChR M4 positive allosteric modulator with EC50 of 197 nM and 437 nM for human and rat M4, respectively.

    物理化学性质&存储条件

    分子量 358.445
    分子式 C22H22N4O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-methyl-4-(4-((6-methylpyridin-3-yl)oxy)piperidin-1-yl)quinoline-3-carbonitrile

    参考文献

    1. Bewley BR, et al. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4274-4279.

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