VU6007496

Chemical Structure : VU6007496

加入收藏

货号: PC-22961Not For Human Use, Lab Use Only.

VU6007496 is a highly selective and CNS penetrant M1 mAChR positive allosteric modulator (PAM) with EC50 of 228 nM (hM1), with minimal M1 agonism (EC50>10 μM).

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

VU6007496 is a highly selective and CNS penetrant M1 mAChR positive allosteric modulator (PAM) with EC50 of 228 nM (hM1), with minimal M1 agonism (EC50>10 μM).
VU6007496 is inactive on human and rat M2–5 (EC50s > 30 μM).
VU6007496 dose-dependently enhanced recognition memory in rats with a minimum effective dose (MED) of 3 mg/kg p.o.

物理化学性质&存储条件

分子量	429.52
分子式	C25H27N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-methyl-7-(4-(1-methyl-1H-pyrazol-3-yl)benzyl)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrrolo[3,2-b]pyridine-5-carboxamide

参考文献

1. Julie L. Engers, et al. ACS Chemical Neuroscience, August 28, 2024

VU6007496

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

VU6007496

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.