VU0152100 |CAS:409351-28-6 Probechem Biochemicals

Chemical Structure : VU0152100

CAS No.: 409351-28-6

加入收藏

VU0152100 (VU152100;VU 0152100;VU-0152100)

货号: PC-43505Not For Human Use, Lab Use Only.

VU0152100 (VU152100) is a potent, selective positive allosteric modulator of M4 mAChR with EC50 of 0.38 uM for rat M4.

规格	价格	库存
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

VU0152100 (VU152100) is a potent, selective positive allosteric modulator of M4 mAChR with EC50 of 0.38 uM for rat M4.
VU0152100 potentiates the M4-mediated calcium response calcium response with maximal shifts of 70-fold with 10 uM in vitro assays.
VU0152100 inhibits behavioral and neurochemical effects of cocaine in vivo, also dose-dependently reverses amphetamine-induced hyperlocomotion in rats and wild-type mice, blocks amphetamine-induced disruption of the acquisition of contextual fear conditioning.

物理化学性质&存储条件

分子量
分子式	C18H19N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethyl-

参考文献

1. Byun NE, et al. Neuropsychopharmacology. 2014 Jun;39(7):1578-93.

2. Brady AE, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):941-53.

3. Dencker D, et al. Psychopharmacology (Berl). 2012 Nov;224(2):277-87.

4. Huynh T, et al. J Med Chem. 2013 Oct 24;56(20):8196-200.

VU0152100 (VU152100;VU 0152100;VU-0152100)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

VU0152100 (VU152100;VU 0152100;VU-0152100)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.