VU-0357017 hydrochloride |CAS:1135242-13-5 Probechem Biochemicals

Chemical Structure : VU-0357017 hydrochloride

CAS No.: 1135242-13-5

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VU-0357017 hydrochloride (VU0357017 hydrochloride)

货号: PC-45705Not For Human Use, Lab Use Only.

VU-0357017 hydrochloride is a subtype-selective allosteric agonist of M1 receptor with EC50 of 198 nM.

规格	价格	库存
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

VU-0357017 hydrochloride is a subtype-selective allosteric agonist of M1 receptor with EC50 of 198 nM.
VU-0357017 displays good selectivity versus M2-M5 and a large panel of GPCRs, ion channels, and transporters.
VU-0357017 shows excellent brain exposure and robust in vivo efficacy in rodent model.

物理化学性质&存储条件

分子量	369.8862
分子式	C18H28ClN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 33 mg/mL
Chemical Name/SMILES	1-Piperidinecarboxylic acid, 4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-, ethyl ester, hydrochloride (1:1)

参考文献

1. Lebois EP, et al. ACS Chem Neurosci. 2010;1(2):104-121.

2. Digby GJ, et al. J Neurosci. 2012 Jun 20;32(25):8532-44.

3. Digby GJ, et al. ACS Chem Neurosci. 2012 Dec 19;3(12):1025-36.

VU-0357017 hydrochloride (VU0357017 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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VU-0357017 hydrochloride (VU0357017 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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