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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-VEST19
VEST19

Chemical Structure : VEST19

CAS No.:

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VEST19

货号: PC-27176Not For Human Use, Lab Use Only.

VEST19 is a potent inhibitor of T. gondii MyoA (TgMyoA) with IC50 of 70 nM, a class XIV myosin motor of apicomplexan parasites, inhibits TgMyoA actin-activated ATPase activity, inhibits the growth of T. gondii in human foreskin fibroblasts (HFFs) with IC50 of 0.366 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

VEST19 is a potent inhibitor of T. gondii MyoA (TgMyoA) with IC50 of 70 nM, a class XIV myosin motor of apicomplexan parasites, inhibits TgMyoA actin-activated ATPase activity, inhibits the growth of T. gondii in human foreskin fibroblasts (HFFs) with IC50 of 0.366 uM.

物理化学性质&存储条件

分子量 349.42
分子式 C15H15N3O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-methoxy-N-((3-(thiophen-2-yl)-1H-pyrazol-4-yl)methyl)benzenesulfonamide

参考文献

1. Anne K Snyder, et al. bioRxiv [Preprint]. 2026 Jun 19:2026.06.18.733251.

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