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首页-小分子抑制剂&激动剂-Others-Spliceosome-UHMCP1
UHMCP1

Chemical Structure : UHMCP1

CAS No.: 2103079-87-2

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UHMCP1

货号: PC-72029Not For Human Use, Lab Use Only.

UHMCP1 is a small molecule that prevents the SF3b155/U2AF65 interaction, binds to the hydrophobic pocket of the U2AF65 UHM domain (Kd=1-20 uM), impacts splicing and cell viability.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    UHMCP1 is a small molecule that prevents the SF3b155/U2AF65 interaction, binds to the hydrophobic pocket of the U2AF65 UHM domain (Kd=1-20 uM), impacts splicing and cell viability.

    物理化学性质&存储条件

    分子量 297.446
    分子式 C19H27N3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (1R,5S)-3-(4-(1H-indol-3-yl)butan-2-yl)-3-azabicyclo[3.2.1]octan-8-amine

    参考文献

    1. Asaki Kobayashi, et al. FEBS J. 2022 Feb;289(3):682-698.

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