UCB-9721 | TgMyoA inhibitor | Probechem Biochemicals

Chemical Structure : UCB-9721

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UCB-9721 (UCB9721)

货号: PC-27175Not For Human Use, Lab Use Only.

UCB-9721 is a potent inhibitor of T. gondii MyoA (TgMyoA) with IC50 of 31 nM, a class XIV myosin motor of apicomplexan parasites, inhibits TgMyoA actin-activated ATPase activity.

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生物&药学活性

UCB-9721 is a potent inhibitor of T. gondii MyoA (TgMyoA) with IC50 of 31 nM, a class XIV myosin motor of apicomplexan parasites, inhibits TgMyoA actin-activated ATPase activity.
UCB-9721 also inhibits TgMyoA motor function in an in vitro motility assay
UCB-9721 inhibits T. gondii parasite motility with IC50 of 0.139 uM, with no detectable toxicity towards mammalian cells.
UCB-9721 inhibits the growth of T. gondii in human foreskin fibroblasts (HFFs) with an IC50 of 2.488 uM.
UCB-9721 also inhibits the motility and/or growth of the related apicomplexan parasites Plasmodium falciparum, Cryptosporidium parvum, and Babesia duncani.

物理化学性质&存储条件

分子量	387.45
分子式	C19H21N3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((3-(4-ethoxyphenyl)-1H-pyrazol-4-yl)methyl)-4-methoxybenzenesulfonamide

参考文献

1. Anne K Snyder, et al. bioRxiv [Preprint]. 2026 Jun 19:2026.06.18.733251.

UCB-9721 (UCB9721)

生物&药学活性

物理化学性质&存储条件

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UCB-9721 (UCB9721)

生物&药学活性

物理化学性质&存储条件

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