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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-Trifluoperazine dihydrochloride
Trifluoperazine dihydrochloride

Chemical Structure : Trifluoperazine dihydrochloride

CAS No.: 440-17-5

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Trifluoperazine dihydrochloride (TFP;SKF5019)

货号: PC-46699Not For Human Use, Lab Use Only.

An antiadrenergic, antidopaminergic and anticholinergic agent.

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500 mg ￥560 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

An antiadrenergic, antidopaminergic and anticholinergic agent; is identified as an inhibitor that disrupts the S100A4/myosin-IIA interaction; block S100A4-mediated disassembly of myosin-IIA filaments, and promote S100A4 oligomerization.

Schizophrenia

Approved

物理化学性质&存储条件

分子量 480.4174
分子式 C21H26Cl2F3N3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2)

参考文献

1. Malashkevich VN, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8605-10.

2. Huerta-Bahena J, et al. Mol Pharmacol. 1983 Jan;23(1):67-70.

3. Creese I, et al. J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):223-6.

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