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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-TCDMC-143160
TCDMC-143160

Chemical Structure : TCDMC-143160

CAS No.: 300813-72-3

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TCDMC-143160 (TCDMC143160)

货号: PC-23626Not For Human Use, Lab Use Only.

TCDMC-143160 is a specific inhibitor of T. cruzi L-threonine dehydrogrenase (TcTDH) with IC50 of 3.5 uM, inhibits the threonine degradation pathway and interferes with parasite growth and viability.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TCDMC-143160 is a specific inhibitor of T. cruzi L-threonine dehydrogrenase (TcTDH) with IC50 of 3.5 uM, inhibits the threonine degradation pathway and interferes with parasite growth and viability.

物理化学性质&存储条件

分子量 271.32
分子式 C16H17NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-N-(4-ethoxyphenyl)-3-(5-methylfuran-2-yl)acrylamide

参考文献

1. Faria JDN, et al. J Biol Chem. 2024 Dec 13:108080.

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