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首页-小分子抑制剂&激动剂-GPCR-Vasopressin Receptor-TASP0434299
TASP0434299

Chemical Structure : TASP0434299

CAS No.: 1520893-08-6

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TASP0434299 (TASP 0434299)

货号: PC-61507Not For Human Use, Lab Use Only.

TASP0434299 is a radioligand candidate for arginine vasopressin 1B (V1B) receptor that exhibits high binding affinities for human and rat V1B receptors with IC50 of 0.526 and 0.641 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TASP0434299 is a radioligand candidate for arginine vasopressin 1B (V1B) receptor that exhibits high binding affinities for human and rat V1B receptors with IC50 of 0.526 and 0.641 nM, respectively.
    TASP0434299 shows no apparent binding affinities for other molecules at 1 uM.

    物理化学性质&存储条件

    分子量 509.607
    分子式 C27H35N5O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-tert-butyl-2-[2-(3-methoxyphenyl)-6-[3-(morpholin-4-yl)propoxy]-4-oxopyrido[2,3-d]pyrimidin-3(4H)-yl]acetamide

    参考文献

    1. Koga K, et al. J Pharmacol Exp Ther. 2016 Jun;357(3):495-508.

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