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首页-小分子抑制剂&激动剂-NF-κB Pathway-TAK1-TAK1-IN-1
TAK1-IN-1

Chemical Structure : TAK1-IN-1

CAS No.: 1356013-39-2

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TAK1-IN-1

货号: PC-62810Not For Human Use, Lab Use Only.

TAK1-IN-1 is a potent, selective, Type I (ATP-competitive, DFG-in) TAK1 inhibitor with Kd of 59 nM, a thienopyrimidine scaffold that serves as a good starting point for medicinal chemistry..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    TAK1-IN-1 is a potent, selective, Type I (ATP-competitive, DFG-in) TAK1 inhibitor with Kd of 59 nM, a thienopyrimidine scaffold that serves as a good starting point for medicinal chemistry.

    物理化学性质&存储条件

    分子量 336.369
    分子式 C17H12N4O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(7-methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide

    参考文献

    1. Miura T, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1031-1036.

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