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首页-小分子抑制剂&激动剂-GPCR-Lysophospholipid Receptor-TAK-615
TAK-615

Chemical Structure : TAK-615

CAS No.: 1664335-55-0

TAK-615 (TAK615)

货号: PC-35273Not For Human Use, Lab Use Only.

TAK-615 (TAK615) is a potent, selective, negative allosteric modulator (NAM) of the LPA1 receptor, partially inhibits the LPA response with IC50 of 91 nM (60% at 10 uM) in calcium mobilisation assays..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TAK-615 (TAK615) is a potent, selective, negative allosteric modulator (NAM) of the LPA1 receptor, partially inhibits the LPA response with IC50 of 91 nM (60% at 10 uM) in calcium mobilisation assays.

物理化学性质&存储条件

分子量 419.452
分子式 C25H22FNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((N-(cyclopropylmethyl)-4-(2-fluorophenoxy)benzamido)methyl)benzoic acid

参考文献

1. Ellery J, et al. Eur J Pharmacol. 2018 May 26;833:8-15.

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