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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-TAK-456
TAK-456

Chemical Structure : TAK-456

CAS No.: 181869-54-5

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TAK-456 (TAK456)

货号: PC-27773Not For Human Use, Lab Use Only.

TAK-456 is an oral triazole with potent and broad-spectrum in vitro antifungal activity shows MIC90 of 0.25 ug/mL against clinical isolates of Candida spp., Aspergillus spp., and Cryptococcus neoformans, except for Candida glabrata.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TAK-456 is an oral triazole with potent and broad-spectrum in vitro antifungal activity shows MIC90 of 0.25 ug/mL against clinical isolates of Candida spp., Aspergillus spp., and Cryptococcus neoformans, except for Candida glabrata.

物理化学性质&存储条件

分子量 481.47
分子式 C22H21F2N9O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(4-(1H-tetrazol-1-yl)phenyl)-3-((2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)imidazolidin-2-one

参考文献

1. Tsuchimori N, et al. Antimicrob Agents Chemother. 2002 May;46(5):1388-93.

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