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首页-小分子抑制剂&激动剂-GPCR-Calcium-sensing Receptor (CaSR)-Strontium ranelate
Strontium ranelate

Chemical Structure : Strontium ranelate

CAS No.: 135459-87-9

Strontium ranelate (Distrontium renelate;S-12911)

货号: PC-45220Not For Human Use, Lab Use Only.

A strontium(II) salt of ranelic acid that stimulates CaSR and leads to the differentiation of pre-osteoblast to osteoblast, increases the bone formation.

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500 mg ¥3680 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A strontium(II) salt of ranelic acid that stimulates CaSR and leads to the differentiation of pre-osteoblast to osteoblast, increases the bone formation; also stimulates osteoblasts to secrete osteoprotegerin in inhibiting osteoclasts formed from pre-osteoclasts in relation to the RANKL system; a medication for osteoporosis treatment.

Osteoporosis

Approved

物理化学性质&存储条件

分子量 513.4896
分子式 C12H6N2O8SSr2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: < 1 mg/mL

Chemical Name/SMILES

3-Thiopheneacetic acid, 5-[bis(carboxymethyl)amino]-2-carboxy-4-cyano-, strontium salt (1:2)

参考文献

1. Hamdy NA. Rheumatology (Oxford). 2009 Oct;48 Suppl 4:iv9-13.

2. Chu JG, et al. BMC Musculoskelet Disord. 2017 Feb 10;18(1):78.

3. Tsai TT, et al. PLoS One. 2017 Jan 4;12(1):e0167296.

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