Sovutrecdeg (CG001419) | TRK degrader | Probechem Biochemicals

Chemical Structure : Sovutrecdeg

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Sovutrecdeg (CG001419, CG-001419)

货号: PC-27503Not For Human Use, Lab Use Only.

Sovutrecdeg (CG001419) is a first-in-class, selective, potent oral degrader of pan-tropomyosin receptor kinase (TRK), selectively degrades both mutant and wild-type TRK proteins.

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生物&药学活性

Sovutrecdeg (CG001419) is a first-in-class, selective, potent oral degrader of pan-tropomyosin receptor kinase (TRK), selectively degrades both mutant and wild-type TRK proteins.

物理化学性质&存储条件

分子量	871.95
分子式	C47H47F2N9O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-[4-[[1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-azetidinyl]methyl]-1-piperazinyl]-2-[(tetrahydro-2H-pyran-4-yl)amino]-

参考文献

1. Patent WO2021170109 A1 2021-09-02.

Sovutrecdeg (CG001419, CG-001419)

生物&药学活性

物理化学性质&存储条件

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Sovutrecdeg (CG001419, CG-001419)

生物&药学活性

物理化学性质&存储条件

参考文献

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