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首页-小分子抑制剂&激动剂-GPCR-mAChR-Solifenacin
Solifenacin

Chemical Structure : Solifenacin

CAS No.: 242478-37-1

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Solifenacin (YM905 free base)

货号: PC-28476Not For Human Use, Lab Use Only.

Solifenacin (YM905 free base) is a potent, M3-preferential muscarinic receptor (mAChR) antagonist with pKi values of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

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100 mg ￥580 In stock
250 mg ￥880 In stock
1 g ￥1480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Solifenacin (YM905 free base) is a potent, M3-preferential muscarinic receptor (mAChR) antagonist with pKi values of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.

物理化学性质&存储条件

分子量 362.47
分子式 C23H26N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-(R)-Quinuclidin-3-yl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

参考文献

1. Uchida T, et al. Br J Clin Pharmacol. 2004 Jul;58(1):4-7.

2. Kobayashi S, et al. Life Sci. 2004 Jan 2;74(7):843-53.

3. Ikeda K, et al. Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):97-103.

4. Kobayashi S, et al. Jpn J Pharmacol. 2001 Jul;86(3):281-8.

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