STING inhibitor H-151 |CAS:941987-60-6 Probechem Biochemicals

Chemical Structure : STING inhibitor H-151

CAS No.: 941987-60-6

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STING inhibitor H-151 (H151)

货号: PC-35312Not For Human Use, Lab Use Only.

STING inhibitor H-151 (H151) is a highly potent, selective, covalent small-molecule antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo.

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5 mg (Free Sample)	￥80	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

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生物&药学活性

STING inhibitor H-151 (H151) is a highly potent, selective, covalent small-molecule antagonist of STING that has noteworthy inhibitory activity both in human cells and in vivo。
The irreversible modification introduced by H-151 to hsSTING again is dependent on Cys91.
H-151 markedly reduces systemic cytokine responses in CMA-treated mice.

物理化学性质&存储条件

分子量	279.343
分子式	C17H17N3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea

参考文献

1. Haag SM, et al. Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0287-8.

STING inhibitor H-151 (H151)

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物理化学性质&存储条件

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STING inhibitor H-151 (H151)

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