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STING inhibitor C-178

Chemical Structure : STING inhibitor C-178

CAS No.: 329198-87-0

STING inhibitor C-178 (STING inhibitor C178)

货号: PC-35310Not For Human Use, Lab Use Only.

STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING.

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5 mg ¥880 In stock
10 mg ¥1280 In stock
25 mg ¥2180 In stock
50 mg ¥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

STING inhibitor C-178 (C178) is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING.
C-178 covalently binds to Cys91, directly targets mouse STING (mmSTING) but not human STING (hsSTING).

物理化学性质&存储条件

分子量 322.276
分子式 C17H10N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide

参考文献

1. Haag SM, et al. Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0287-8.

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