Chemical Structure : STING inhibitor C-178
CAS No.: 329198-87-0
货号: PC-35310Not For Human Use, Lab Use Only.
STING inhibitor C-178 is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING.
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---|---|---|---|
5 mg | ¥880 | In stock | |
10 mg | ¥1280 | In stock | |
25 mg | ¥2180 | In stock | |
50 mg | ¥3580 | In stock | |
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STING inhibitor C-178 (C178) is a covalent, small-molecule inhibitor of STING, blocks palmitoylation (PMA)-induced clustering of STING.
C-178 covalently binds to Cys91, directly targets mouse STING (mmSTING) but not human STING (hsSTING).
分子量 | 322.276 | |
分子式 | C17H10N2O5 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide |
1. Haag SM, et al. Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0287-8.
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