STING activator Compound 11

Chemical Structure : STING activator Compound 11

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货号: PC-73369Not For Human Use, Lab Use Only.

STING activator Compound 11 is a potent, small molecule activator/agonist of human STING with EC50 of 66 nM (HEK, R232).

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

STING activator Compound 11 is a potent, small molecule activator/agonist of human STING with EC50 of 66 nM (HEK, R232).
Compound 11 showed significantly enhanced potency compared with G10.

物理化学性质&存储条件

分子量	492.464
分子式	C24H17F5N2O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(3,5-difluorobenzyl)-2-methyl-3-oxo-N-(2,4,6-trifluorobenzyl)-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide

参考文献

1. Monali Banerjee, et al. PLoS One. 2020 Sep 10;15(9):e0237743.