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首页-小分子抑制剂&激动剂-GPCR-Adrenergic Receptor-SR59230A
SR59230A

Chemical Structure : SR59230A

CAS No.: 174689-39-5

SR59230A (SR-59230A)

货号: PC-22239Not For Human Use, Lab Use Only.

SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50 of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SR59230A is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50 of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively.

物理化学性质&存储条件

分子量 389.48
分子式 C21H19N5OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-aminophenyl)-4-[1-(2-thiophen-3-ylethyl)-1H-[1],[2],[3]triazol-4-yl]benzamide

参考文献

1. Nisoli E, et al. Mol Pharmacol. 1996 Jan;49(1):7-14.

2. Manara L, et al. Br J Pharmacol. 1996 Feb;117(3):435-442.

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