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首页-小分子抑制剂&激动剂-GPCR-Adrenergic Receptor-SOM3355
SOM3355

Chemical Structure : SOM3355

CAS No.: 42864-78-8

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SOM3355 (Bevantolol hydrochloride)

货号: PC-26994Not For Human Use, Lab Use Only.

Bevantolol hydrochloride (SOM3355) is a CNS-permeant, selective β1-adrenergic receptor antagonist with pKi value of 7.83 in rat cerebral cortex, also shows additional VMAT2 and VMAT1 inhibition activity.

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50 mg ￥580 In stock
100 mg ￥880 In stock
250 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bevantolol hydrochloride (SOM3355) is a CNS-permeant, selective β1-adrenergic receptor antagonist with pKi value of 7.83 in rat cerebral cortex, also shows additional VMAT2 and VMAT1 inhibition activity.

物理化学性质&存储条件

分子量 381.90
分子式 C20H28ClNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-((3,4-Dimethoxyphenethyl)amino)-3-(m-tolyloxy)propan-2-ol hydrochloride

参考文献

1. Gamez J, et al. Br J Clin Pharmacol. 2023 May;89(5):1656-1664.

2. Turilli-Ghisolfi ES, et al. Front Pharmacol. 2026 May 19;17:1824708.

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