Chemical Structure : SJPYT-195
货号: PC-49310Not For Human Use, Lab Use Only.
SJPYT-195 is a small molecule glue degrader (PROTAC) of the translation termination factor GSPT1, consists of SPA70 derivative to ligandof the E3 substrate receptor cereblon (CRBN), causes subsequent reduction of PXR protein.
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SJPYT-195 is a small molecule glue degrader (PROTAC) of the translation termination factor GSPT1, consists of SPA70 derivative to ligand of the E3 substrate receptor cereblon (CRBN), causes subsequent reduction of PXR protein.
分子量 | 666.691 | |
分子式 | C35H34N6O8 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Andrew D Huber, et al. ACS Med Chem Lett. 2022 Jul 15;13(8):1311-1320.
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