SJ988497 | JAKs PROTAC | Probechem Biochemicals

Chemical Structure : SJ988497

CAS No.: 2595365-41-4

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货号: PC-49143Not For Human Use, Lab Use Only.

SJ988497 is a highly potent JAKs degarder proteolysis-targeting chimera (PROTAC), potently kills CRLF2r ALL cell lines (MHH-CALL-4, IC50=0.4 nM).

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SJ988497 is a highly potent JAKs degarder proteolysis-targeting chimera (PROTAC), potently kills CRLF2r ALL cell lines (MHH-CALL-4, IC50=0.4 nM).

分子量	688.749
分子式	C36H36N10O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)-4-((4-(1-propyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)benzamide

1. Yunchao Chang, et al. Blood. 2021 Dec 9;138(23):2313-2326.