SIAIS630121 | NAMPT PROTAC | Probechem Biochemicals

Chemical Structure : SIAIS630121

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SIAIS630121 (NAMPT PROTAC)

货号: PC-22771Not For Human Use, Lab Use Only.

SIAIS630121 is a highly selective NAMPT-targeted PROTAC that promote rapid and potent degradation of iNAMPT and eNAMPT in a cereblon-dependent manner.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

SIAIS630121 is a highly selective NAMPT-targeted PROTAC that promote rapid and potent degradation of iNAMPT and eNAMPT in a cereblon-dependent manner.

物理化学性质&存储条件

分子量	826.06
分子式	C49H59N7O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(4-(1-(4-(4-(8-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oct-7-yn-1-yl)piperazin-1-yl)benzoyl)piperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide

参考文献

1. Xiaotong Zhu, et al. Cell Chem Biol. 2022 Nov 17;29(11):1616-1629.e12.