SGC-CK2-2 | CK2 inhibitor | Probechem Biochemicals

Chemical Structure : SGC-CK2-2

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SGC-CK2-2 (CK2 inhibitor, Casein kinase 2 inhibitor)

货号: PC-22407Not For Human Use, Lab Use Only.

SGC-CK2-2 is a potent, selective casein kinase 2 (CSNK2, CK2) chemical probe inhibitor with IC50 of 0.2 uM, shows much improved kinase selectivity compared with silmitasertib (CX-4945).

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100 mg		Get quote

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生物&药学活性

SGC-CK2-2 is a potent, selective casein kinase 2 (CSNK2, CK2) chemical probe inhibitor with IC50 of 0.2 uM, shows much improved kinase selectivity compared with silmitasertib (CX-4945).
SGC-CK2-2 shows high selectivity (3/403 kinases) in DiscoverX KINOMEscan showing 90% inhibition at 1 µM.
SGC-CK2-2 demonstrated inhibition of viral replication with IC50 of 10-20 uM in MHV-NLuc in DBT cells.

物理化学性质&存储条件

分子量	330.35
分子式	C19H14N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(benzylamino)pyrimido[4,5-c]quinoline-8-carboxylic acid

参考文献

1. Asressu KH, et al. Pharmaceuticals (Basel). 2024 Feb 27;17(3):306.

SGC-CK2-2 (CK2 inhibitor, Casein kinase 2 inhibitor)

生物&药学活性

物理化学性质&存储条件

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SGC-CK2-2 (CK2 inhibitor, Casein kinase 2 inhibitor)

生物&药学活性

物理化学性质&存储条件

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