SGC-CK2-1 analog 2h

Chemical Structure : SGC-CK2-1 analog 2h

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货号: PC-20908Not For Human Use, Lab Use Only.

SGC-CK2-1 analog 2h is potent, selective and in vivo active inhibitor of casein kinase 2α (CSNK2A, CK2α) with pIC50 of 7.5 and 7.7 against CSNK2A1 and CSNK2A2, respectively.

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1 g		Get quote

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生物&药学活性

SGC-CK2-1 analog 2h is potent, selective and in vivo active inhibitor of casein kinase 2α (CSNK2A, CK2α) with pIC50 of 7.5 and 7.7 against CSNK2A1 and CSNK2A2, respectively.
SGC-CK2-1 analog 2h inhibits mouse β-CoV replication using an MHV-nLuc assay in DBT cells with pIC50 of 7.1.

物理化学性质&存储条件

分子量	432.49
分子式	C22H24N8O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	CC(NC1=CC(NC2=NC3=C(C#N)C=NN3C(NC4CC4)=C2)=CC=C1N5CCOCC5)=O

参考文献

1. Yang X, et al. bioRxiv. 2023 May 18:2023.05.15.540828.