S1P1 Agonist 8 |CAS:1324003-64-6 Probechem Biochemicals

Chemical Structure : S1P1 Agonist 8

CAS No.: 1324003-64-6

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S1P1 Agonist 8 (S1P1 agonist III )

货号: PC-43245Not For Human Use, Lab Use Only.

S1P1 Agonist 8 is a potent, selective, orally bioavailable S1P1 receptor agonist with EC50 of 35 nM (S1P1 internalization), >100-fold selectivity over against receptor subtypes S1P2-5.

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5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
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生物&药学活性

S1P1 Agonist 8 is a potent, selective, orally bioavailable S1P1 receptor agonist with EC50 of 35 nM (S1P1 internalization), >100-fold selectivity over against receptor subtypes S1P2-5。
S1P1 Agonist 8 induces dose-dependent reduction in lymphocyte count in rats.

物理化学性质&存储条件

分子量	415.3652
分子式	C21H16F3N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Pyridinecarboxamide, 4-methoxy-N-[[[2-(trifluoromethyl)[1,1'-biphenyl]-4-yl]amino]carbonyl]-

参考文献

1. Harrington PE, et al. ACS Med Chem Lett. 2011 Nov 23;3(1):74-8.

2. Pennington LD, et al. ACS Med Chem Lett. 2011 Jul 29;2(10):752-7.

S1P1 Agonist 8 (S1P1 agonist III )

生物&药学活性

物理化学性质&存储条件

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S1P1 Agonist 8 (S1P1 agonist III )

生物&药学活性

物理化学性质&存储条件

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