S118 | S1P2 receptor antagonist | Probechem Biochemicals

Chemical Structure : S118

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S118 (S-118, S1P2 receptor antagonist)

货号: PC-27966Not For Human Use, Lab Use Only.

S118 is a potent, selective antagonist of sphingosine-1-phosphate receptor 2 (S1P2 receptor), attenuates idiopathic pulmonary fibrosis (IPF) through anti-inflammatory, anti-fibrosis, and anti-EMT effects.

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生物&药学活性

S118 is a potent, selective antagonist of sphingosine-1-phosphate receptor 2 (S1P2 receptor), attenuates idiopathic pulmonary fibrosis (IPF) through anti-inflammatory, anti-fibrosis, and anti-EMT effects.

物理化学性质&存储条件

分子量	446.27
分子式	C19H14Cl2FN7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,6-dichloropyridin-4-yl)-2-(4-(4-fluorophenyl)-1-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazine-1-carboxamide

参考文献

1. Mu SY, et al. Br J Pharmacol. 2026 Feb;183(4):957-972.

2. Shao HB, et al. Br J Pharmacol. 2026 Oct;183(19):5854-5870.

S118 (S-118, S1P2 receptor antagonist)

生物&药学活性

物理化学性质&存储条件

参考文献

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S118 (S-118, S1P2 receptor antagonist)

生物&药学活性

物理化学性质&存储条件

参考文献

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