Ruxuplam (SKY-0515) | HTT splicing modulator | Probechem Biochemicals

Chemical Structure : Ruxuplam

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Ruxuplam (SKY-0515, SKY0515)

货号: PC-27494Not For Human Use, Lab Use Only.

Ruxuplam (SKY-0515) is a small molecule splicing modulator to lower mHTT and post-meiotic segregation 1 (PMS1), shows potential for treatment of Huntington disease.

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生物&药学活性

Ruxuplam (SKY-0515) is a small molecule splicing modulator to lower mHTT and post-meiotic segregation 1 (PMS1), shows potential for treatment of Huntington disease.

物理化学性质&存储条件

分子量	397.45
分子式	C21H24FN5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Benzoxazolol, 6-[6-[[(1R,2R,3S,5S)-2-fluoro-9-azabicyclo[3.3.1]non-3-yl]methylamino]-3-pyridazinyl]-2-methyl-

参考文献

1. Patent WO2025255218 A1 2025-12-11.

2. Patent WO2025006878 A1 2025-01-02.

Ruxuplam (SKY-0515, SKY0515)

生物&药学活性

物理化学性质&存储条件

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Ruxuplam (SKY-0515, SKY0515)

生物&药学活性

物理化学性质&存储条件

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