欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-GPCR-Calcium-sensing Receptor (CaSR)-Ronacaleret
Ronacaleret

Chemical Structure : Ronacaleret

CAS No.: 753449-67-1

加入收藏

Ronacaleret (SB-751689;SB751689)

货号: PC-61505Not For Human Use, Lab Use Only.

Ronacaleret (SB751689) is a potent calcium sensing receptor (CaSR) negative allosteric modulator with IC50 of 146 nM for hCaSR.

规格 价格 库存 数量
5 mg ￥4880 In stock
10 mg ￥7880 In stock
25 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ronacaleret (SB751689) is a potent calcium sensing receptor (CaSR) negative allosteric modulator with IC50 of 146 nM for hCaSR.
Ronacaleret (SB751689) stimulates parathyroid hormone (PTH) release and increases bone formation markers.
Ronacaleret (SB751689) act as an effective oral anabolic agent to enhance fracture healing.

物理化学性质&存储条件

分子量 447.523
分子式 C25H31F2NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-[3-[(2R)-3-[[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]-4,5-difluorophenyl]propanoic acid

参考文献

1. Balan G, et al. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3328-32.

2. Fitzpatrick LA, et al. J Clin Endocrinol Metab. 2011 Aug;96(8):2441-9.

3. Fitzpatrick LA, et al. Bone. 2011 Oct;49(4):845-52.

4. Caltabiano S, et al. Bone. 2013 Sep;56(1):154-62.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: