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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-Rezafungin
Rezafungin

Chemical Structure : Rezafungin

CAS No.: 1396640-59-7

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Rezafungin (CD101)

货号: PC-38031Not For Human Use, Lab Use Only.

Rezafungin (CD101) is a long-acting novel echinocandin possesses potent antibiofilm activity against early and mature candida albicans biofilms.

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5 mg ￥2880 In stock
10 mg ￥4880 In stock
50 mg ￥11800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Rezafungin (CD101) is a long-acting novel echinocandin possesses potent antibiofilm activity against early and mature candida albicans biofilms.
CD101 (0.25 or 1 μg/ml) significantly prevented adhesion-phase cells from developing into mature biofilms and eradicated preformed mature biofilms.
CD101 stopped the growth of adhesion- and early-phase biofilms within minutes.

物理化学性质&存储条件

分子量 1226.41
分子式 C63H85N8O17+
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(((2R,6S,9S,11R,12R,14aS,15S,16S,20S,25aS)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6,20-bis((R)-1-hydroxyethyl)-16-methyl-5,8,14,19,22,25-hexaoxo-9-(4''-(pentyloxy)-[1,1':4',1''-terphenyl]-4-carboxamido)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl)oxy)-N,N,N-trimethylethan-1-aminium

参考文献

1. Chandra J, et al. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01750-17.

2. Sofjan AK, et al. J Glob Antimicrob Resist. 2018 Sep;14:58-64.

3. Arendrup MC, et al. Clin Microbiol Infect. 2018 Nov;24(11):1200-1204.

4. Lakota EA, et al. Antimicrob Agents Chemother. 2018 May 25;62(6):e02603-17.

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